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The different types of hyaluronic acid and how to choose them?

différents types acide hyaluronique

Hyaluronic acid has become a star ingredient in cosmetics. You see it on many products, but did you know that there are different types of hyaluronic acid? Each has specific properties that act differently on the skin. Let’s discover these differences together to help you make the best choice.


What is hyaluronic acid?

Hyaluronic acid is a molecule naturally present in our bodies. It is found mainly in the skin, joints and eyes. It is a polysaccharide (a type of carbohydrate) with a remarkable capacity to retain water.

In our skin, it plays an essential role in tissue hydration and elasticity. Unfortunately, its production declines with age. This decline contributes to the appearance of signs of skin ageing.

In cosmetics, hyaluronic acid is used for its moisturizing properties and plumping effect. It helps maintain skin hydration and reduce the appearance of fine lines.


Different types of hyaluronic acid by molecular weight

The main difference between hyaluronic acid types lies in their molecular weight. This characteristic determines the size of the molecules and their ability to penetrate the different layers of the skin.

High molecular weight hyaluronic acid

High-molecular-weight hyaluronic acid has large molecules. Because of their size, these molecules cannot penetrate the deeper layers of the skin.

They remain on the surface, forming a protective film that :

  • Creates a barrier against external aggression
  • Reinforces the skin’s hydrolipidic film
  • Moisturizes the surface layer of the epidermis
  • Smoothes fine dehydration lines

This type of hyaluronic acid is ideal for protecting skin against pollution and the sun. It provides immediate visible hydration.

Medium molecular weight hyaluronic acid

This form of hyaluronic acid is obtained by fractioning the molecule into medium-sized pieces.

It penetrates slightly deeper than the high molecular weight form and :

  • Stores in the skin’s connective tissue
  • Prevents water from evaporating
  • Regulates dehydration
  • Improves skin elasticity

Low molecular weight hyaluronic acid

Low-molecular-weight hyaluronic acid has much smaller molecules. This form can penetrate deeper into the epidermis.

Its benefits include :

  • Deeper penetration of epidermal layers
  • Stimulating natural hyaluronic acid production
  • More intense skin nutrition
  • Preventing sagging skin

This is the preferred type of hyaluronic acid for anti-aging treatments targeting wrinkles.

Other forms of hyaluronic acid

Acetylated hyaluronic acid

This lesser-known form has both hydrophilic (water-attracting) and lipophilic (fat-attracting) properties. Scientific research has shown that it can absorb more water than ordinary hyaluronic acid.

Cross-linked hyaluronic acid

Cross-linked hyaluronic acid is obtained by a specific chemical process. This modification creates a highly stable molecule with great water-holding capacity.

This form is mainly used in aesthetic injections to fill wrinkles and create volume.


How to choose the right type of hyaluronic acid for your skin

For dry skin

Dry skin naturally lacks moisture. They need a reinforcement of their cutaneous barrier. For this type of skin, choose :

  • A combination of high- and low-molecular-weight hyaluronic acid
  • Formulas that combine hyaluronic acid with agents that prevent water evaporation

Hyaluronic acid provides deep hydration while improving the skin’s appearance.

For oily or combination skin

Contrary to popular belief, oily skin also needs hydration. Hyaluronic acid is particularly well-suited as it moisturizes without adding oil.

For this type of skin, opt for :

  • Low molecular weight hyaluronic acid
  • Lightweight formulas

Hyaluronic acid helps regulate sebum production and prevent shine.

For sensitive skin

Sensitive skin can also benefit from hyaluronic acid. Studies have shown that even low-molecular-weight hyaluronic acid is well tolerated by this type of skin.

For sensitive skin, choose :

  • High-molecular-weight hyaluronic acid, which remains on the surface
  • Simple, fragrance- and alcohol-free formulations

Hyaluronic acid has soothing properties that help reduce skin sensitivity.

For mature skin

To fight the signs of aging, the ideal choice would be :

  • A combination of hyaluronic acids with different molecular weights
  • Formulas combining hyaluronic acid with other anti-ageing active ingredients

To target wrinkles, low-molecular-weight hyaluronic acid will be more effective as it penetrates deeper[2].


Application methods: topical vs. injectable

Topical hyaluronic acid treatments

Cosmetic products containing hyaluronic acid are applied directly to the skin. Their advantages:

  • Easy, risk-free daily use
  • Immediate skin hydration
  • Gradual improvement in skin condition

To maximize the effectiveness of topical skincare products, apply them to slightly damp skin. This allows the molecule to capture water on the surface, amplifying its moisturizing power.

Hyaluronic acid injections

Hyaluronic acid injections are part of aesthetic medicine. They deliver more visible, longer-lasting results, but require the intervention of a qualified professional[6].

Injections are mainly used for :

  • Filling in deep wrinkles
  • Redefining facial contours
  • Increase lip volume
  • Improve the appearance of certain scars

The effects of injections generally last from 6 to 18 months, depending on the area treated[6].

Efficiency differences

Applied topically, hyaluronic acid increases hydration of the stratum corneum by around 10%. The effects are rapidly visible for hydration, but anti-aging benefits appear after around 4 weeks of regular use.

Injections offer immediate and more pronounced results. They work deeper into the dermis and are more effective in treating established wrinkles[6].


Myths and facts about hyaluronic acid

Myth 1: Hyaluronic acid dries out the skin

Not true. This idea often stems from incorrect application. Hyaluronic acid is a powerful moisturizer, but it works by attracting water.

Myth 2: Hyaluronic acid is an exfoliant

Although the term “acid” may be misleading, hyaluronic acid has no exfoliating action.

Myth 3: Hyaluronic acid is only for dry skin

Hyaluronic acid is suitable for all skin types, including oily and combination skin.

Myth 4: All hyaluronic acids are the same

As we have seen, there are different types of hyaluronic acid, depending on their molecular weight. Each has specific properties and effects.

Myth 5: Hyaluronic acid can hydrate the skin on its own

For optimum benefits, hyaluronic acid must be used in conjunction with other moisturizing ingredients. It attracts moisture, but this hydration must be sealed with a cream to prevent water from evaporating.


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